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Merck
모든 사진(1)

주요 문서

SAB4500935

Sigma-Aldrich

Anti-FOXO1 antibody produced in rabbit

affinity isolated antibody

동의어(들):

FKHR, FOXO1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, forkhead box O1A (FKHR)

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 69 kDa

종 반응성

mouse, human

농도

~1 mg/mL

기술

ELISA: 1:1000
immunohistochemistry: 1:50-1:100

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... FOXO1(2308)

일반 설명

Anti-FOXO1 Antibody detects endogenous levels of total FOXO1 protein.
FOXO1 (forkhead box O1) encodes a forkhead transcription factor that belongs to the Foxo subfamily. It is located on human chromosome 13q14. FOXO1 is abundantly expressed in adult pancreas and partially expressed in pancreatic β cells.

면역원

The antiserum was produced against synthesized peptide derived from human FOXO1/3/4.

Immunogen Range: 15-64

생화학적/생리학적 작용

FOXO1 (forkhead box O1) blocks the separation of cell in fetal pancreatic progenitor cells. It controls the differentiation of adipocyte. It plays a major role in the development and multiplication of β cell. It plays an important role in transferring insulin signaling downstream of protein kinase B.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Forkhead Protein FoxO1 Acts as a Repressor to Inhibit Cell Differentiation in Human Fetal Pancreatic Progenitor Cells
Jiang Z, et al.
Journal of Diabetes Research, 2017 (2017)
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
Daitoku H, et al.
Proceedings of the National Academy of Sciences of the USA, 101(27), 10042-10047 (2004)
The forkhead transcription factor Foxo1 regulates adipocyte differentiation
Nakae J, et al.
Developmental Cell, 4(1), 119-129 (2003)
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth
Kitamura T, et al.
The Journal of Clinical Investigation, 110(12), 1839-1847 (2002)
Dense pattern of embryonal rhabdomyosarcoma, a lesion easily confused with alveolar rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group
Rudzinski ER, et al.
American Journal of Clinical Pathology, 140(1), 82-90 (2013)

질문

후기

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활성 필터

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