SAB4500888

Anti-FGFR3 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): CD333, CD333 antigen, FGFR-3, Fibroblast growth factor receptor 3, JTK4
• MDL number: MFCD02096346
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 87 kDa
• 종 반응성: rat, mouse, human
• 농도: ~1 mg/mL
• 기술: ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P22607
• UniProt 수납 번호: P22607
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... FGFR3(2261)

설명

일반 설명

Anti-FGFR3 Antibody detects endogenous levels of total FGFR3 protein.

FGFR3 (fibroblast growth factor receptor 3) belongs to the fibroblast growth factor receptor (Fgfr) family of proteins. It has 19 exons, an extracellular ligand binding domain, a transmembrane domain and an intracellular tyrosine kinase domain. It is located on human chromosome 4p16.3.

면역원

The antiserum was produced against synthesized peptide derived from human FGFR3.

Immunogen Range: 131-180

애플리케이션

Anti-FGFR3 antibody has been used in immunohistochemistry.

생화학적/생리학적 작용

Germline mutations in FGFR3 (fibroblast growth factor receptor 3) results in autosomal dominant skeletal dysplasias like achondroplasia (ACH), thanatophoric dysplasia (TD) and hypochrondroplasia (HCH). The gene also controls cellular activity.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable