SAB4500423

Anti-ADORA2A antibody produced in rabbit

affinity isolated antibody

• 동의어(들): ADORA2, ADORA2A, Adenosine receptor A2a
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 44 kDa
• 종 반응성: human
• 농도: ~1 mg/mL
• 기술: ELISA: 1:1000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P29274
• UniProt 수납 번호: P29274
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ADORA2A(135)

설명

일반 설명

Anti-ADORA2A Antibody detects endogenous levels of total ADORA2A protein.

Adenosine A2a receptor (ADORA2A) is a G protein-coupled receptor. It is highly expressed in the brain. It is located on human chromosome 22q11.23.

면역원

The antiserum was produced against synthesized peptide derived from human ADORA2A.

Immunogen Range: 321-370

생화학적/생리학적 작용

Activation of the adenosine A2a receptor (ADORA2A) prevents T-cell proliferation and production of pro-inflammatory cytokines. It functions in increasing cytosolic cAMP levels. The protein has been associated with stimulation of liver ischemic preconditioning. ADORA2A is also linked to dermal fibrosis and scleroderma.

특징 및 장점

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물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable