SAB4500090
Anti-ADARB1 antibody produced in rabbit
affinity isolated antibody
동의어(들):
RNA-editing deaminase 1, RNA-editing enzyme 1, dsRNA adenosine deaminase
로그인조직 및 계약 가격 보기
크기 선택
100 μG
₩796,572
₩796,572
예상 입고일2025년 7월 04일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
모든 사진(1)
크기 선택
보기 변경
100 μG
₩796,572
About This Item
₩796,572
예상 입고일2025년 7월 04일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 80 kDa
종 반응성
rat, mouse, human
농도
~1 mg/mL
기술
ELISA: 1:20000
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... ADARB1(104)
관련 카테고리
일반 설명
Adenosine deaminase, RNA specific B1 (ADARB1) is encoded by the gene mapped to human chromosome 21q22.3, a region associated with familial bipolar disorder. ADARB1 is characterized with two double-stranded RNA-binding domains and a deaminase domain involved in editing action.
면역원
The antiserum was produced against synthesized peptide derived from human ADARB1.
Immunogen Range: 481-530
Immunogen Range: 481-530
생화학적/생리학적 작용
Adenosine deaminase, RNA specific B1 (ADARB1) enzyme plays a vital role in editing pre-mRNA of glutamate receptor B subunit. Combined effect of ADARB1 and HTR2C (5-Hydroxytryptamine Receptor 2C) variants contribute to the suicide attempt (SA) vulnerability in psychiatric patients. ADARB1 is a candidate gene for neurological diseases, such as bipolar affective disorder and epilepsy. Decrease in the activity of ADAR2 enzyme results in α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor-mediated death of motor neurons in mice. ADARB1 enzyme is expressed consistently in carcinomas and sarcomas, and it is upregulated in lymphomas and seminomas when compared to normal tissues.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Genomics screen in transformed stem cells reveals RNASEH2A, PPAP2C, and ADARB1 as putative anticancer drug targets.
Flanagan JM, et al.
Molecular Cancer Therapeutics, 8(1), 249-260 (2009)
Sequence analysis of ADARB1 gene in patients with familial bipolar disorder.
Amore M, et al.
Journal of Affective Disorders, 81(1), 79-85 (2004)
Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2.
Hideyama T, et al.
The Journal of Neuroscience, 30(36), 11917-11925 (2010)
Joint effect of ADARB1 gene, HTR2C gene and stressful life events on suicide attempt risk in patients with major psychiatric disorders.
Karanovic J, et al.
The World Journal of Biological Psychiatry : The Official Journal of the World Federation of Societies of Biological Psychiatry, 16(4), 261-271 (2015)
L Mittaz et al.
Genomics, 41(2), 210-217 (1997-04-15)
RED1 is a double-stranded RNA-specific editase characterized in the rat and is implicated in the editing of glutamate receptor subunit pre-mRNAs, particularly in the brain. Starting from human ESTs homologous to the rat RED1 sequence, we have characterized two forms
활성 필터
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