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Merck
모든 사진(1)

문서

SAB4301578

Sigma-Aldrich

Anti-phospho-ERK1/2 (pThr202/Tyr204) antibody produced in rabbit

affinity isolated antibody

동의어(들):

ERK-1, ERK1, ERT2, P44ERK1, PRKM3

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

42 kDa
44 kDa

종 반응성

rat, mouse, human

농도

1.0 mg/mL

기술

western blot: 1:500-1:1000 (Cell Lysate)

동형

IgG

수납 번호(accession number)

NP_001035145.1 

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

phosphorylation (pThr202/pTyr204)

유전자 정보

human ... MAPK3(5595)

특이성

The antibody detects endogenous level of p44/42 MAP Kinase only when phosphorylated at Threonine 202 and Tyrosine 204 .

면역원

Peptide sequence around phosphorylation site of Threonine 202/Tyrosine 204(F-L-T(p)-E-Y(p)-V-A) derived from Human p44/42 MAP Kinase.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Varun Kumar et al.
Current eye research, 46(5), 710-718 (2020-10-28)
Understanding molecular changes is essential for designing effective treatments for nonarteritic anterior ischemic optic neuropathy (AION), the most common acute optic neuropathy in adults older than 50 years. We investigated changes in the mitogen-activated protein kinase (MAPK) pathway after experimental AION
Lenka Halova et al.
Open biology, 11(4), 200405-200405 (2021-04-08)
Fluctuations in TOR, AMPK and MAP-kinase signalling maintain cellular homeostasis and coordinate growth and division with environmental context. We have applied quantitative, SILAC mass spectrometry to map TOR and nutrient-controlled signalling in the fission yeast Schizosaccharomyces pombe. Phosphorylation levels at
Vittorio Perfetti et al.
Oncotarget, 8(34), 56158-56167 (2017-09-17)
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs express the receptor tyrosine kinase KIT, and the majority of GISTs present KIT gain-of-function mutations that cluster in the 5' end of the receptor juxtamembrane
Ravinder K Goyal et al.
BMC genomics, 19(1), 178-178 (2018-03-07)
The mitogen-activated protein kinase (MAPK) family is involved in signal transduction networks that underpin many different biological processes in plants, ranging from development to biotic and abiotic stress responses. To date this class of enzymes has received little attention in
Guangchao Zhao et al.
Rejuvenation research, 22(4), 325-334 (2018-11-10)
It is known that preconditional treatment with volatile anesthetics can induce tolerance of the brain to stroke. A previous study demonstrated that the involvement of TREK-1, a two-pore domain K+ channel, in sevoflurane preconditioning induced neuroprotection against focal cerebral ischemia

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