SAB4300425

Anti-GRIN2B (Ab-1474) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): Anti-MGC142178 antibody produced in rabbit, Anti-MGC142180 antibody produced in rabbit, Anti-NMDAR2B antibody produced in rabbit, Anti-NR2B antibody produced in rabbit, Anti-glutamate receptor, ionotropic, N-methyl D-aspartate 2B antibody produced in rabbit
• MDL number: MFCD00243314
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: ~190 kDa
• 종 반응성: human, rat, mouse
• 농도: 1 mg/mL
• 기술: indirect immunofluorescence: 1:100-1:200
• 동형: IgG
• 면역원 서열: (H-V-Y-E-K)
• NCBI 수납 번호: NP_000825.2
• UniProt 수납 번호: Q13224
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... GRIN2B(2904)

설명

일반 설명

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) codes for N-methyl d-aspartate receptor subtype 2B (GluN2B). It belongs to the N-methyl-D-aspartate receptor (NMDAR) gene family. It is located on human chromosome 12p13.1.

면역원

Peptide sequence around aa. 1472-1476 (H-V-Y-E-K), according to the protein GRIN2B.

생화학적/생리학적 작용

GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) plays an important role in the growth of neurons and is highly essential for the learning and memory. GRIN2B mutation is associated with neuropsychiatric and developmental disorders like schizophrenia, Parkinson′s disease and bipolar disorder.

특징 및 장점

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표적 설명

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable