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Merck
모든 사진(1)

주요 문서

SAB4300419

Sigma-Aldrich

Anti-CDKN1A (Ab-145) antibody produced in rabbit

affinity isolated antibody

동의어(들):

Anti-CAP20 antibody produced in rabbit, Anti-CDKN1 antibody produced in rabbit, Anti-CIP1 antibody produced in rabbit, Anti-MDA-6 antibody produced in rabbit, Anti-cyclin-dependent kinase inhibitor 1A (p21, Cip1) antibody produced in rabbit

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

~21 kDa

종 반응성

human

농도

1 mg/mL

기술

western blot: 1:500-1:1000

동형

IgG

면역원 서열

(R-Q-T-S-M)

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... CDKN1A(1026)

면역원

Peptide sequence around aa. 143-147 (R-Q-T-S-M), according to the protein CDKN1A.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

표적 설명

May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.

물리적 형태

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Xiaojun Shu et al.
Molecular medicine reports, 19(6), 5195-5202 (2019-05-07)
MicroRNAs (miRNAs) are considered to be critical mediators of gene expression with respect to tumor progression, although their role in ischemia‑induced angiogenesis is poorly characterized, including in peripheral arterial disease (PAD). Furthermore, the underlying mechanism of action of specific miRNAs
Xiang Li et al.
Oxidative medicine and cellular longevity, 2019, 9706792-9706792 (2019-03-27)
Multiple signaling pathways including ERK, PI3K-Akt, and NF-κB, which are essential for onset and development of cancer, can be activated by intracellularly sustained high levels of H2O2 provided by elevated activity and expression of copper/zinc superoxide dismutase (SOD1) that catalyzes

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