SAB4300400
Anti-PRKD1 (Ab-910) antibody produced in rabbit
affinity isolated antibody
동의어(들):
Anti-PKC-MU antibody produced in rabbit, Anti-PKCM antibody produced in rabbit, Anti-PKD antibody produced in rabbit, Anti-PRKCM antibody produced in rabbit, Anti-protein kinase D1 antibody produced in rabbit
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크기 선택
100 μG
₩694,260
₩694,260
예상 입고일2025년 6월 18일세부사항
모든 사진(1)
크기 선택
보기 변경
100 μG
₩694,260
About This Item
₩694,260
예상 입고일2025년 6월 18일세부사항
추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
~115 kDa
종 반응성
human, mouse
농도
1 mg/mL
기술
western blot: 1:500-1:1000
동형
IgG
면역원 서열
(R-V-S-I-L)
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... PRKD1(5587)
일반 설명
PRKD1 gene encodes PKD1 (protein kinase D1), that belongs to the protein kinase D family. It is a serine/threonine kinase, which is expressed in cells of the normal mammary gland. The PRKD1 gene promoter has a great CpG island covering 1.2kb, including the transcription start site and the entire exon 1.
면역원
Peptide sequence around aa. 908-912 (R-V-S-I-L), according to the protein PRKD1.
생화학적/생리학적 작용
PRKD1 (Protein kinase D 1) is a negative modulator of cell migration . It plays an important role in cell adhesion, cell migration, vesicle transport, cell survival , signal transduction, membrane trafficking and immune function. It preserves the epithelial phenotype by inhibiting epithelial-to-mesenchymal transition.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
표적 설명
Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.
물리적 형태
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis
Borges S, et al.
Breast Cancer Research, 15(2) (2013)
Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands
Weinreb I, et al.
Nature Genetics, 46(11), 1166-1169 (2014)
The AR/NCOA1 axis regulates prostate cancer migration by involvement of PRKD1
Luef B, et al.
Endocrine-Related Cancer, 23(6), 495-508 (2016)
Molecular cloning, epigenetic regulation, and functional characterization of Prkd1 gene promoter in dopaminergic cell culture models of Parkinson's disease.
Ay M
Journal of Neurochemistry, 135(2), 402-415 (2015)
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
