추천 제품
결합
peroxidase conjugate
항체 형태
IgG fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
설명
Research area: Microbiome
양식
lyophilized powder
분자량
~33 kDa
종 반응성
Staphylococcus aureus (alpha-Toxin (a-Hemolysin) )
농도
~4 mg/mL
기술
direct ELISA: 1:2,000-1:4,000 using 1 μg/mL Staphylococcal alpha-Toxin (a-Hemolysin) for coating.
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
Staphylococcus aureus subsp. aureus NCTC 8325 ... SAOUHSC_01121(3920722)
일반 설명
Staphylococcal alpha-Toxin is a pore forming cytotoxin. Native alpha toxin is a water-soluble monomer but later on gets converted to β-barrel in the host membranes. It is 34 kDa protein. The N- terminal and the C-terminal are involved in forming a membrane-binding epitope and the central domain forms a membrane-inserting, pore forming domain.
특이성
Anti-Staphylococcal alpha-Toxin-peroxidase antibody specifically recognizes Staphylococcal alpha-Toxin (?-Hemolysin) and has no cross reactivity with Staphylococcal Enterotoxin A (SEA), Cholera Toxin or Pseudomonas Exotoxin A
면역원
purified toxin from Staphylococcus aureus
애플리케이션
The antibody may be used in various immunochemical techniques including ELISA
생화학적/생리학적 작용
Staphylococcal alpha-Toxin plays a role in binding to the host membrane. At higher concentrations it makes the cells which are devoid of receptors to become more permeable and hence also to protein-free lipid bilayers.
진단 영향
Unless otherwise stated in our catalog our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
물리적 형태
Supplied as a lyophilized powder.
저장 및 안정성
Store the lyophilized product at 2–8 °C. For extended storage after reconstitution, keep at –20 °C in working aliquots. Avoid repeated freeze-thaw cycles. For continuous use after reconstitution, keep at 2–8 °C for up to 1 month. Solutions at working dilution should be discarded if not used within 12 hours.
면책조항
For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.


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Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Staphylococcal alpha-toxin, streptolysin-O, and Escherichia coli hemolysin: prototypes of pore-forming bacterial cytolysins
Bhakdi S, et al.
Archives of Microbiology, 165(2), 73-79 (1996)
Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus alpha-hemolysin-mediated cellular injury
Wilke GA and Wardenburg JB
Proceedings of the National Academy of Sciences of the USA, 107(30), 13473-13478 (2010)
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