SAB4200519

Anti-GLUT1 (C-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 동의어(들): Anti-SLC2A1, Anti-member 1, Anti-solute carrier family 2 (facilitated glucose transporter)
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen ~55-70 kDa
• 종 반응성: mouse, rat, human
• 농도: ~1.0 mg/mL
• 기술: western blot: 0.5-1.0 μg/mL using rat spinal cord extracts (S1 fraction)
• UniProt 수납 번호: P11166
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SLC2A1(6513) ; mouse ... Slc2a1(20525) ; rat ... Slc2a1(24778)

설명

일반 설명

Glucose transporter 1 (GLUT1, SLC2A1) belongs to the family of glucose transporters (GLUTs). It is localized to the membrane and is highly expressed in the brain and spinal cord, with a relative high density in the cerebellum. The vascular form of GLUT1 is mainly localized in endothelial cells of blood vessels.

면역원

peptide corresponding to a sequence at the C-terminus of human GLUT1, conjugated to KLH. The corresponding sequence is identical in rat and mouse GLUT1.

애플리케이션

Anti-GLUT1 (C-terminal) antibody produced in rabbit has been used in immunoblotting.

생화학적/생리학적 작용

GLUT1 is the main glucose transporter in the blood-brain barrier (BBB), which regulates basal glucose levels. Increased expression of GLUT1 is associated with cell growth and in malignant transformation.

물리적 형태

solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable