추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen ~55 kDa
종 반응성
rat, mouse, human
향상된 검증
recombinant expression
Learn more about Antibody Enhanced Validation
농도
~1.0 mg/mL
기술
immunohistochemistry: 20 μg/mL using formalin-fixed, paraffin-embedded rat brain
western blot: 1.5-3 μg/mL using U937 cell extracts
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... ARC(23237)
mouse ... Arc(11838)
rat ... Arc(54323)
일반 설명
Activity regulated cytoskeleton associated protein (Arc) is encoded by the gene mapped to human chromosome 8q24.3.
면역원
synthetic peptide corresponding to a sequence at the C-terminal region of human Arc, conjugated to KLH. The corresponding sequence is identical in rat and mouse Arc.
생화학적/생리학적 작용
Activity regulated cytoskeleton associated protein (Arc) plays a vital role in memory formation. It also facilitates activity-dependent plasticity of dendrites. Mutation in the gene has been associated with the development of idiopathic generalized epilepsy (IGE).
물리적 형태
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
Insulin-induced expression of the activity-regulated cytoskeleton-associated gene (ARC) in human neuroblastoma cells requires p21ras, mitogen-activated protein kinase/extracellular regulated kinase and src tyrosine kinases but is protein kinase C-independent
Kremerskothen J
Neuroscience Letters, 321, 153-156 (2002)
Mutation screening of the chromosome 8q24.3-human activity-regulated cytoskeleton-associated gene (ARC) in idiopathic generalized epilepsy.
Haug K
Molecular and Cellular Probes, 14, 255-260 (2000)
G L Lyford et al.
Neuron, 14(2), 433-445 (1995-02-01)
Neuronal activity is an essential stimulus for induction of plasticity and normal development of the CNS. We have used differential cloning techniques to identify a novel immediate-early gene (IEG) cDNA that is rapidly induced in neurons by activity in models
Joseph Phan et al.
Scientific reports, 10(1), 13611-13611 (2020-08-14)
The two hypothalamic neuropeptides oxytocin and melanin concentrating hormone (MCH) share several physiological actions such as the control of maternal care, sexual behavior, and emotions. In this study, we uncover the role for the oxytocin-MCH signaling pathway in mood regulation.
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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