SAB4200450
Anti-SOX11 (C-terminal) antibody produced in rabbit
IgG fraction of antiserum
동의어(들):
Anti-SRY (sex determining region Y)-box 11
로그인조직 및 계약 가격 보기
크기 선택
200 μL
₩682,486
₩682,486
예상 입고일2025년 7월 24일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
모든 사진(3)
크기 선택
보기 변경
200 μL
₩682,486
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
₩682,486
예상 입고일2025년 7월 24일세부사항
기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요
추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
IgG fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
rat, human
기술
immunohistochemistry: 1:100-1:200 using formalin-fixed paraffin-embedded rat brain and cerebellum.
indirect immunofluorescence: 1:100-1:200 using human HeLa cells.
western blot: 1:4000-1:8000 using whole extracts of HEK-293T cells overexpressing human recombinant SOX11
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... SOX11(6664)
일반 설명
Sex determining region Y (SRY)-box 11 (SOX11) protein belongs to the SRY-related high mobility group (HMG)-box (SOX) family of transcription factors. This protein is localized in adult immature neurons but is normally not expressed in any other adult tissue. SOX11 gene is located on the human chromosome 2p25.2.
특이성
Anti-SOX11 (C-terminal) recognizes human and rat SOX11.
면역원
peptide corresponding to the C-terminal region of human SOX11, conjugated to KLH. The corresponding sequence is identical in monkey, bovine and pig and differs by a single amino acid in mouse and rat.
애플리케이션
Anti-SOX11 (C-terminal) antibody produced in rabbit may be used in:
- immunoblotting
- immunofluorescence
- immunohistochemistry
생화학적/생리학적 작용
Sex determining region Y (SRY)-box 11 (SOX11) plays a role in the regulation of tissue remodeling during embryogenesis which is essential for neurogenesis. This protein is also involved in tumorigenesis. SOX11 protein also plays a role in the determination of cell fate. Upregulation of the SOX11 gene leads to ovarian cancer, brain tumor, medulloblastomas and gliomas. This protein functions as a biomarker in mantle cell lymphoma (MCL), acute lymphoblastic leukemia (ALL) and Burkitt lymphomas (BL).
물리적 형태
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
저장 및 안정성
For continuous use, store at 2-8°C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Esther Palomino Lago et al.
Animals : an open access journal from MDPI, 14(1) (2024-01-11)
Fractures caused by bone overloading are a leading cause of euthanasia in Thoroughbred racehorses. The risk of fatal fracture has been shown to be influenced by both environmental and genetic factors but, to date, no specific genetic mechanisms underpinning fractures
Maria Carmela Vegliante et al.
PloS one, 6(6), e21382-e21382 (2011-07-09)
Recent studies have shown aberrant expression of SOX11 in various types of aggressive B-cell neoplasms. To elucidate the molecular mechanisms leading to such deregulation, we performed a comprehensive SOX11 gene expression and epigenetic study in stem cells, normal hematopoietic cells
Xiao Wang et al.
PloS one, 5(11), e14085-e14085 (2010-12-03)
The SRY (sex determining region Y)-box 11 (SOX11) gene, located on chromosome 2p25, encodes for a transcription factor that is involved in tissue remodeling during embryogenesis and is crucial for neurogenesis. The role for SOX11 in hematopoiesis has not yet
Lakshmi Pillai-Kastoori et al.
PLoS genetics, 10(7), e1004491-e1004491 (2014-07-11)
Ocular coloboma is a sight-threatening malformation caused by failure of the choroid fissure to close during morphogenesis of the eye, and is frequently associated with additional anomalies, including microphthalmia and cataracts. Although Hedgehog signaling is known to play a critical
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