SAB4200181

Anti-PMP70 antibody, Mouse monoclonal

clone 70-18, purified from hybridoma cell culture

• 동의어(들): Anti- ZWS2; ZELLWEGER SYNDROME 2, Anti-70 kDa Peroxisomal membrane Protein, Anti-ABCD3, Anti-ATP-binding cassette, sub-family D (ALD), member 3, Anti-PXMP1
• MDL number: MFCD01865555
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 70-18, monoclonal
• 양식: buffered aqueous solution
• 분자량: antigen ~70 kDa
• 종 반응성: rat, mouse, human
• 포장: antibody small pack of 25 μL
• 향상된 검증: independent; Learn more about Antibody Enhanced Validation
• 농도: ~1.0 mg/mL
• 기술: immunofluorescence: suitable; western blot: 1-2 μg/mL using whole extracts of human HepG2 or rat PC12 cells
• 동형: IgG1
• UniProt 수납 번호: P28288
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ABCD3(5825) ; mouse ... Abcd3(19299) ; rat ... Abcd3(25270)

설명

일반 설명

Anti-PMP70 antibody, Mouse monoclonal (mouse IgG1 isotype) is derived from the hybridoma 70-18 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. The 70 kDa peroxisomal membrane protein (PMP70), also designated PXMP1 and ABCD3 or ABD3, is one of the major components of peroxisomal membranes. PMP70 belongs to the ALD subfamily of the ATP binding cassette (ABC) transporter superfamily. It is a half-size ABC integral membrane protein consisting of 6 transmembrane domains and one ATP-binding domain.

애플리케이션

Anti-PMP70 antibody, Mouse monoclonal has been used in immunoblotting[1] and immunofluorescence.

생화학적/생리학적 작용

The 70 kDa peroxisomal membrane protein (PMP70) participates in the metabolic transport of long and very long fatty acids into peroxisomes. It forms a stable complex with the adrenoleukodystrophy protein, adrenoleukodystrophy protein (ALDP), and several other peroxisomal proteins. Mutations in the PMP70 (PXMP1) gene may cause a subset of Zellweger syndrome-2, an autosomal recessive disorder that is manifested by defective import mechanisms for peroxisomal matrix enzymes.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable