SAB4200132

Anti-ULK3 antibody produced in rabbit

~1 mg/mL, affinity isolated antibody

• 동의어(들): Anti-unc-51-like kinase 3
• UNSPSC 코드: 12352203
• NACRES: NA.44

속성

• 생물학적 소스: rabbit
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen ~50 kDa
• 종 반응성: human
• 포장: antibody small pack of 25 μL
• 농도: ~1 mg/mL
• 기술: western blot: 1-2 μg/mL using whole extracts of human U87 cells
• UniProt 수납 번호: Q6PHR2
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ULK3(25989)

설명

일반 설명

Anti-ULK3 is produced in rabbit using as the immunogen a synthetic peptide corresponding to a fragment of human ULK3, conjugated to KLH. Unc-51-like kinase 3 (ULK3) belongs to the ULK family of serine/threonine kinases. ULK3 is an autophagy related protein with an N-terminal kinase domain, which shows high similarity to those of ULK1 and ULK2. ULK3 localizes to the elongating isolation membrane upon autophagy activation.

애플리케이션

Anti-ULK3 antibody produced in rabbit has been used in immunoblotting.

생화학적/생리학적 작용

Unc-51-like kinase 3 (ULK3) controls abscission timing in response to lagging chromosomes. Overexpression of ULK3 induces autophagy and senescence. ULK3 is also a positive regulator of the Hedgehog signalling pathway.

물리적 형태

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable