SAB2900053
Anti-NR4A1 (AB1) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
동의어(들):
Ngfi-b, gfrp1, nak-1, nak1, nerve growth factor inducible-B protein
로그인조직 및 계약 가격 보기
크기 선택
50 μG
₩1,106,655
₩1,106,655
예상 입고일2025년 7월 04일세부사항
모든 사진(1)
크기 선택
보기 변경
50 μG
₩1,106,655
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
₩1,106,655
예상 입고일2025년 7월 04일세부사항
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
human
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... NR4A1(3164)
일반 설명
Nuclear receptor subfamily 4 group A member 1 (NR4A1) is a transcription factor expressed in thymocytes. It is part of an orphan nuclear receptor superfamily. The gene encoding this protein is localized on human chromosome 12.
면역원
Synthetic 17 amino acid peptide from internal region of human NUR77. Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Horse (100%); Gorilla, Dog, Bat, Panda (94%); Marmoset, Bovine (88%); Mouse, Rat (82%).
생화학적/생리학적 작용
Nuclear receptor subfamily 4 group A member 1 (NR4A1) has a role in cell proliferation. It acts as an activator of mechanistic target of rapamycin (mTOR) signaling and regulates apoptosis. The protein modulates genes related to low oxidative stress and growth promotion. NR4A1 has been shown to be expressed in ovarian tumors.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Solution in phosphate-buffered saline containing less than 0.1% sodium azide.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells.
Ashouri JF and Weiss A
Journal of Immunology, 198(2) (2017)
Differential Copy Number Aberrations in Novel Candidate Genes Associated with Progression from In Situ to Invasive Ductal Carcinoma of the Breast
Shaoxi Liao
Genes Chromosomes Cancer (2012)
Nuclear receptor subfamily 4, group A, member 1 inhibits extrinsic apoptosis and reduces caspase-8 activity in H2O2-induced human HUC-F2 fibroblasts.
Shimuzu Y
Redox Report (2015)
High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome.
Delgado E
Gynecologic Oncology, 141(2) (2016)
Lingli He et al.
Cell reports, 33(3), 108284-108284 (2020-10-22)
The Hippo signaling pathway maintains organ size and tissue homeostasis via orchestration of cell proliferation and apoptosis. How this pathway triggers cell apoptosis remains largely unexplored. Here, we identify NR4A1 as a target of the Hippo pathway that mediates the
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
