SAB1407309

Anti-FGF21 antibody produced in mouse

purified immunoglobulin, buffered aqueous solution

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen ~22.3 kDa
• 종 반응성: human, rat
• 기술: western blot: 1 μg/mL
• NCBI 수납 번호: BC018404
• UniProt 수납 번호: Q9NSA1
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... FGF21(26291)

설명

일반 설명

FGF (fibroblast growth factor) family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The function of this growth factor has not yet been determined. The gene is mapped to human chromosome 19q13.33 and codes for a member of FGF superfamily. The encoded protein is produced in liver.

면역원

FGF21 (AAH18404.1, 1 a.a. ~ 209 a.a) full-length human protein.

Sequence
MDSDETGFEHSGLWVSVLAGLLLGACQAHPIPDSSPLLQFGGQVRQRYLYTDDAQQTEAHLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPEACSFRELLLEDGYNVYQSEAHGLPLHLPGNKSPHRDPAPRGPARFLPLPGLPPAPPEPPGILAPQPPDVGSSDPLSMVGPSQGRSPSYAS

생화학적/생리학적 작용

The members of FGF (fibroblast growth factor) family take part in cell survival and mitogenic activities. FGFs are associated with a number of physiological processes such as cell growth, morphogenesis, embryonic development, tissue repair, tumor growth and invasion. FGF21 is a hormonal factor that regulates glucose homeostasis and energy metabolism. It possesses anti-diabetic properties by mediating glucose uptake in peripheral tissues. It also exhibits autocrine effects in white adipose tissue. FGF21 is present in milk and is needed for intestinal function in the neonate. It is also associated with bone loss. FGF21 is considered hepatoprotective in nature.

물리적 형태

Solution in phosphate buffered saline, pH 7.4

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable