SAB1306492
ANTI-ZO1(C-TERMINAL) antibody produced in rabbit
purified immunoglobulin, buffered aqueous solution
동의어(들):
TJP1, Tight junction protein 1, Tight junction protein ZO-1, ZO1, Zona occludens protein 1
로그인조직 및 계약 가격 보기
크기 선택
400 μL
₩694,666
₩694,666
구입 가능 여부는 고객센터에 문의하십시오.
모든 사진(1)
크기 선택
보기 변경
400 μL
₩694,666
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
₩694,666
구입 가능 여부는 고객센터에 문의하십시오.
추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
195459 Da
종 반응성
human
기술
flow cytometry: 1:10-1:50
immunohistochemistry: 1:50-1:100
western blot: 1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TJP1(7082)
일반 설명
Tight junction protein 1 (TJP1) or zona occludens protein 1 (ZO1) is an adaptor protein. It acts as a scaffold protein between the tight junction and actin cytoskeleton. ZO1 has a molecular weight of 220kDa and is part of the membrane-associated guanylate kinase homolog family. The protein possesses three PDZ domains at its amino terminal, an SH3 domain and a region which bears homology to guanylate kinase. The ZO1 gene is localized on human chromosome 15q13.1.
애플리케이션
ANTI-ZO1(C-TERMINAL) antibody produced in rabbit has been used in immunofluorescence.
생화학적/생리학적 작용
Tight junction protein 1 (TJP1) or zona occludens protein 1 (ZO1) has a role in the formation of epithelial lumens. It interacts with occludin and modulates tight junction barrier regulation. ZO1 is also involved in the formation of the odontoblast layer and in actomyosin cytoskeleton regulation. Low expression of ZO1 has been linked to increased cell invasiveness in breast cancer, colorectal cancer and digestive tract cancers.
물리적 형태
Supplied in PBS with 0.09% (W/V) sodium azide
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation.
Tornavaca O, et al.
Journal of Cellular Biochemistry (2015)
Genome-wide association study of patient and clinician rated global impression severity during antipsychotic treatment
Shaunna L, et al.
Pharmacogenetics and Genomics (2013)
Novel role of zonula occludens-1: A tight junction protein closely associated with the odontoblast differentiation of human dental pulp cells.
Xu J, et al.
Cell Biol. (2016)
ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture.
Odenwald MA, et al.
Journal of Cell Science (2017)
Increased ZO-1 expression predicts valuable prognosis in non-small cell lung cancer.
International Journal of Clinical and Experimental Pathology (2013)
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
