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Merck
모든 사진(1)

주요 문서

SAB1303013

Sigma-Aldrich

ANTI-IL17RB (CENTER) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

동의어(들):

Cytokine receptor CRL4, EVI27, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17RB, IL-17Rh1, IL17BR, IL17RB, IL17Rh1, Interleukin-17 receptor B, Interleukin-17B receptor, UNQ2501/PRO19612

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크기 선택

400 μL
₩757,190

₩757,190


예상 입고일2025년 9월 01일세부사항

기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요


크기 선택

보기 변경
400 μL
₩757,190

About This Item

UNSPSC 코드:
12352203
NACRES:
NA.43

₩757,190


예상 입고일2025년 9월 01일세부사항

기존과 동일한 품질을 인하된 가격으로 - 어려운 예산 상황을 머크와 함께 극복하세요

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

IgG fraction of antiserum

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

55885 Da

종 반응성

human

기술

flow cytometry: 1:10-1:50
immunohistochemistry: 1:50-1:100
western blot: 1:250-1:500

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... IL17RB(55540)

일반 설명

Interleukin 17 receptor B (IL-17RB) belongs to the IL-17 receptor family. IL17RB, the receptor for interleukin 17 B (IL17B) is expressed at a high level in the liver, kidney, and other peripheral organs. It is also expressed in memory and effector T lymphocytes. IL17RB gene is located on human chromosome 3p21.1.

애플리케이션

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

생화학적/생리학적 작용

Interleukin 17 receptor B (IL-17RB) might be considered in thyroid cancer therapy as a potential therapeutic target. IL17RB exhibits much efficient binding avidity to interleukin 17 E (IL17E). IL-17RB is overexpressed in pancreatic, gastric, and prostate cancers.

물리적 형태

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Alfonso Lavorgna et al.
PLoS pathogens, 10(10), e1004418-e1004418 (2014-10-24)
Human T-cell leukemia virus type 1 (HTLV-1) infection is linked to the development of adult T-cell leukemia (ATL) and the neuroinflammatory disease HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-1 Tax protein functions as a potent viral oncogene that constitutively
Qingli Bie et al.
Scientific reports, 6, 25447-25447 (2016-05-06)
Inflammation is a critical component involved in tumor progression. Interleukin-17 (IL-17) belongs to a relatively new family of cytokines that has been associated with the progression of cancers. However, the role of IL-17B/IL-17RB (IL-17 receptor B) signaling to stemness of
Lei Ren et al.
Molecular immunology, 90, 126-135 (2017-07-18)
IL-17RB, a member of the IL-17 receptor family that can be activated by IL-17B, has been proved to be involved in inflammatory diseases and cancers. However, the function of IL-17RB in thyroid cancer is still unknown. In this study, IL-17RB
Gary M Hunninghake et al.
BMC pulmonary medicine, 11, 17-17 (2011-04-09)
The relationships between total serum IgE levels and gene expression patterns in peripheral blood CD4+ T cells (in all subjects and within each sex specifically) are not known. Peripheral blood CD4+ T cells from 223 participants from the Childhood Asthma

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