The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, anbapoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis.
면역원
FASTK (NP_006703, 1-40) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FASTK.
물리적 형태
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.