EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in the gene for EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.
면역원
EDA (NP_001390, 143-177) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human EDA.
물리적 형태
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.