UBTD1 contains a ubiquitin domain, and has been demonstrated to bind to p53 in cells p53 is linked to the ubiquitination pathway through its transcriptional regulation of the four ubiquitin ligases, MDM2, COP1, Siah1b, and Pirh2. The role of UBTD1 has not been elucidated, however preliminary evidence indicates a potential role in p53 signaling.
면역원
UBTD1 (NP_079230, 163-200) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human UBTD1.
물리적 형태
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.