S8071

Salvinorin A

≥98% (HPLC), solid

• 동의어(들): (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
• 실험식(Hill 표기법): C₂₃H₂₈O₈
• CAS Number: 83729-01-5
• Molecular Weight: 432.46
• MDL number: MFCD05664742
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24899776
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 약물 제어: regulated under CDSA - not available from Sigma-Aldrich Canada
• 저장 조건: protect from light
• 색상: white
• solubility: DMSO: ≥10 mg/mL; ethanol: ~3 mg/mL
• 저장 온도: −20°C
• SMILES string: [H][C@@]12CC[C@@]3(C)[C@@H](C[C@H](OC(C)=O)C(=O)[C@]3([H])[C@@]1(C)C[C@H](OC2=O)c4ccoc4)C(=O)OC
• InChI: 1S/C23H28O8/c1-12(24)30-16-9-15(20(26)28-4)22(2)7-5-14-21(27)31-17(13-6-8-29-11-13)10-23(14,3)19(22)18(16)25/h6,8,11,14-17,19H,5,7,9-10H2,1-4H3/t14-,15-,16-,17-,19-,22-,23-/m0/s1
• InChI key: OBSYBRPAKCASQB-AGQYDFLVSA-N
• 유전자 정보: human ... OPRD1(4985) , OPRK1(4986) , OPRM1(4988) ; rat ... Oprk1(29335)

설명

애플리케이션

Salvinorin A was administered to rats to study effects on lactic acid-stimulated stretching.¹

생화학적/생리학적 작용

Salvanorin A is a non-nitrogenous κ opioid receptor agonist.

Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (K_i=4.3 nm) and cloned (K_i=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.

특징 및 장점

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)