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Merck
모든 사진(1)

주요 문서

S150

Sigma-Aldrich

Spermine–Nitric oxide complex

source of nitric oxide

동의어(들):

N-[4-[1-(3-Aminopropyl)-2-hydroxy-2-nitrosohydrazino]butyl]-1,3-propanediamine, SPER/NO, Spermine NONOate

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About This Item

실험식(Hill 표기법):
C10H26N6O2
CAS Number:
Molecular Weight:
262.35
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:

Quality Level

형태

powder

저장 조건

desiccated

색상

white

solubility

methanol: ≥1 mg/mL
H2O: ≥2 mg/mL

εmax

8500 at 252 nm

배송 상태

dry ice

저장 온도

−20°C

SMILES string

NCCCN(N(N=O)O)CCCCNCCCN

InChI

1S/C10H26N6O2/c11-5-3-8-13-7-1-2-9-15(10-4-6-12)16(18)14-17/h13,18H,1-12H2

InChI key

QPIOUFBAROSIAN-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Used to produce a controlled release of nitric oxide in solution.

기타 정보

air sensitive

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Thais de Castro Barbosa et al.
Metabolism: clinical and experimental, 62(1), 79-89 (2012-08-15)
The amino acid Arginine (Arg) is the main biological precursor of nitric oxide (NO) and has been described to improve insulin sensitivity in diabetes and obesity. We investigated the molecular mechanisms involved in the long-term effects of Arg on glucose
A S Deshmukh et al.
Diabetologia, 53(6), 1142-1150 (2010-03-30)
We investigated the direct effect of a nitric oxide donor (spermine NONOate) on glucose transport in isolated human skeletal muscle and L6 skeletal muscle cells. We hypothesised that pharmacological treatment of human skeletal muscle with N-(2-aminoethyl)-N-(2-hydroxy-2-nitrosohydrazino)-1,2-ethylenediamine (spermine NONOate) would increase
Payam Dibaj et al.
Glia, 58(9), 1133-1144 (2010-05-15)
To understand the pathomechanisms of spinal cord injuries will be a prerequisite to develop efficient therapies. By investigating acute lesions of spinal cord white matter in anesthetized mice with fluorescently labeled microglia and axons using in vivo two-photon laser-scanning microscopy
Fang Cheng et al.
Cancer letters, 273(1), 148-154 (2008-09-12)
Here we demonstrate a synergistic and tumor selective cytotoxic effect by combined treatment with naphthoxylosides, polyamine synthesis inhibitor, and polyamine based nitric oxide (NO) donor, using in vitro human tumor models. We have earlier reported that heparan sulfate priming naphthoxyloside
Travis J Bourret et al.
Scientific reports, 7(1), 15083-15083 (2017-11-10)
The PhoPQ two-component regulatory system coordinates the response of Salmonella enterica serovar Typhimurium to diverse environmental challenges encountered during infection of hosts, including changes in Mg

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