S1300

Monoclonal Anti-L-Selectin (CD62L) antibody produced in mouse

2 mg/mL, clone FMC46, purified immunoglobulin, buffered aqueous solution

• 동의어(들): Monoclonal Anti-CD62L, Anti-L-Selectin
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: FMC46, monoclonal
• 양식: buffered aqueous solution
• 분자량: antigen 74-95 kDa
• 종 반응성: human
• 농도: 2 mg/mL
• 기술: flow cytometry: suitable; immunohistochemistry (frozen sections): suitable
• 동형: IgG2b
• UniProt 수납 번호: P14151
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SELL(6402)

설명

특이성

Recognizes the CD62L (L-Selectin, LAM-1, Leu8, TQ1, LECAM-1, LECCAM-1, DREG) surface antigen. The antibody recognizes an epitope localized to the lectin domain. It inhibits "rolling" interactions and significantly reduces the binding of FITC-yeast phosphomannan monoester core polysaccharide to lymphocytes, monocytes and neutrophils.
5^th Workshop: Code No. S061

면역원

human PHA-activated peripheral blood mononuclear cells.

표적 설명

CD62L, a glycoprotein and member of the selectin family of adhesion receptors, is constitutively expressed on all classes of leukocytes including lymphocytes, monocytes, and polymorphonuclear cells. It is expressed on myeloid progenitor cells, erythroid precursor cells, and some thymocytes.

물리적 형태

Solution, 0.2 μm filtered, in 0.01 M phosphate buffered saline, pH 7.4.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves