RAB1320

Human Cathepsin Z ELISA

for serum, plasma and cell culture supernatants

• UNSPSC 코드: 12352200

속성

• 종 반응성: human
• 기술: ELISA: suitable
• 입력: sample type serum; sample type plasma; sample type cell culture supernatant(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... CTSZ(1522)

설명

일반 설명

Cathepsins are normally localized in lysosomes of almost all mammalian cells, but under certain conditions they can be secreted from the cells that take part in local proteolysis.[1][2] Cathepsin Z is a cysteine protease, predominantly expressed in immune cells including monocytes, macrophages or dendritic cells.[3][4][5]

This ELISA antibody pair detects Human Cathepsin Z (CTSZ/Cathepsin X/Cathepsin P)

애플리케이션

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

생화학적/생리학적 작용

Cathepsins are lysosomal proteases that play an important role in the intracellular degradation of exogenous and endogenous proteins, activation of enzyme precursors, and tumor invasion and metastasis.[6] Cathepsin Z is known to be associated with the pathogenesis of cancer and promotes the development and proliferation of tumor cells. Cathepsin Z mediates the process of proliferation, migration, maturation, adhesion, signal transduction and phagocytosis of immune cells.[3][4][5]

기타 정보

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

안전성 정보

• 픽토그램: GHS05
• 신호어: Warning
• 유해 및 위험 성명서: H290
• 예방조치 성명서: P234 - P390
• Hazard Classifications: Met. Corr. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable