가격 및 재고 정보를 현재 이용할 수 없음 고객지원팀으로 연락바랍니다.
추천 제품
종 반응성
human
기술
ELISA: suitable
입력
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... BAMBI(25805)
일반 설명
BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) gene codes for a transmembrane glycoprotein which is a pseudo receptor belonging to the family of TGF-β (transforming growth factor β receptor) type I receptors.[1][2] BAMBI is predominantly expressed in placenta, spleen and kidney medulla and also found liver, prostate, gut and kidney cortex.[1]
This ELISA antibody pair detects Human BAMBI. Other species not yet determined.
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
생화학적/생리학적 작용
BAMBI (bone morphogenic protein and activin membrane-bound inhibitor) acts as an inhibitor of TGF-β (transforming growth factor β receptor) signalling which causes epithelial-mesenchymal transition.[1] Upregulation of BAMBI gene is observed in chronic obstructive pulmonary disease and a number of cancer including thyroid, liver, colorectal cancer and ovarian cancer.[3][4] BAMBI might regulate the events of inflammation and remodeling processes.[3]
기타 정보
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Dysregulation of the Transforming Growth Factor β Pathway in Induced Pluripotent Stem Cells Generated from Patients with Diamond Blackfan Anemia
Jingping G, et al.
PLoS ONE, 10(8), e0134878-e0134878 (2015)
Downregulation of the TGFβ Pseudoreceptor BAMBI in Non?Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.
Marwitz S, et al.
Cancer Research (2016)
LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia
Yao H, et al.
Scientific Reports, 6, 27051-27051 (2016)
Kai Liu et al.
Molecular medicine reports, 10(2), 874-880 (2014-06-11)
The upregulation of bone morphogenetic protein and activin membrane‑bound inhibitor (BAMBI) has been observed in several types of malignant cancer, including thyroid, ovarian, liver and colorectal cancer. However, the pathological role and the regulatory mechanism of BAMBI in gastric cancer
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.
