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추천 제품
종 반응성
human
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
입력
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8.2 pg/mL
standard curve range: 8.19-2000 pg/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... ANGPTL3(27329)
일반 설명
Angiopoietin-related protein 3 (ANGPTL3) is a member of the ANGPTL family and is expressed in the liver.[1] The ANGPTL3 gene is mapped on the human chromosome at 1p31.3.[2] Mutations in the ANGPTL3 gene lead to familial combined hypolipidemia, a Mendelian condition that is indicated by lower levels of triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein cholesterol.[3] The ANGPTL3 enzyme-linked immunosorbent assay (ELISA) kit provides for the quantitative measurement of angiopoietin-related protein 3 in cell culture supernatants, plasma, and serum.
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Maria Fernanda Garcés et al.
Scientific reports, 10(1), 21118-21118 (2020-12-05)
This study aimed to determine ANGPTL3 serum levels in healthy young lean and obese non-diabetic men during an oral glucose tolerance test (OGTT) and correlate them with anthropometric, biochemical and hormonal parameters. A case-control study was carried out and 30
Fabiana Quagliarini et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(48), 19751-19756 (2012-11-15)
Angiopoietin-like proteins (ANGPTLs) play major roles in the trafficking and metabolism of lipids. Inactivation of ANGPTL3, a gene located in an intron of DOCK7, results in very low levels of LDL-cholesterol (C), HDL-C and triglyceride (TAG). We identified another ANGPTL
Junpeng Ma et al.
Frontiers in oncology, 10, 1382-1382 (2020-09-15)
Meningiomas, as the most common primary tumor of the central nervous system, are known to harbor genomic aberrations that associate with clinical phenotypes. Here we performed genome-wide genotyping for cranial meningiomas in 383 Chinese patients and identified 9,821 copy-number variations
Nathan O Stitziel et al.
Journal of the American College of Cardiology, 69(16), 2054-2063 (2017-04-08)
Familial combined hypolipidemia, a Mendelian condition characterized by substantial reductions in all 3 major lipid fractions, is caused by mutations that inactivate the gene angiopoietin-like 3 (ANGPTL3). Whether ANGPTL3 deficiency reduces risk of coronary artery disease (CAD) is unknown. The study
Oleg Kovrov et al.
Journal of lipid research, 60(4), 783-793 (2019-01-29)
Angiopoietin-like (ANGPTL) 8 is a secreted inhibitor of LPL, a key enzyme in plasma triglyceride metabolism. It was previously reported that ANGPTL8 requires another member of the ANGPTL family, ANGPTL3, to act on LPL. ANGPTL3, much like ANGPTL4, is a
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