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추천 제품
종 반응성
human
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
capture ELISA: suitable
입력
sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 50 pg/mL
standard curve range: 102.4-10000 pg/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
human ... FGF2(2247)
일반 설명
The Human bFGF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human bFGF in serum, plasma, cell culture supernatants and urine.
면역원
Recombinant Human basic-FGF
애플리케이션
Human bFGF ELISA kit has been used:
- to quantify the level of residual cytokines in decellularized meningeal scaffolds (DMS)[1]
- to measure cytokine levels in acellularized meningeal scaffolds (AMS) and recovered meningeal tissues (RMS/CMS)[2]
- to analyze basic-fibroblast growth factor (bFGF) concentration in cell culture medium[3]
생화학적/생리학적 작용
FGF2 (fibroblast growth factor 2, also referred to as BFGF (basic fibroblast growth factor)) interacts with FGFR1 (fibroblast growth factor receptor 1), FGFR2 and FGFR3.[4] It stimulates the proliferation of a wide variety of cells, including mesenchymal, neuroectodermal and endothelial cells.[5][6][7] FGF2 also determines the fate of neural precursor cells and promotes neuronal axon regeneration. It plays an important role in spinal cord injury repair.[8] FGF2 is known to stimulate angiogenesis and is associated with cancer development.[9] High levels of FGF2 are present in the kidney of children with HIV (human immunodeficiency virus)-renal diseases.[10] MicroRNA (miR)-503 targets FGF2 mRNA and inhibits migration and invasiveness of osteosarcoma (OS) cells.[11]
기타 정보
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
키트 구성품 역시 별도로 이용 가능함
제품 번호
설명
SDS
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
FGF2 plays a key role in embryonic cerebrospinal fluid trophic properties over chick embryo neuroepithelial stem cells.
Martin C
Developmental Biology, 297(2), 402-416 (2006)
Xiaohua Liu et al.
Psychiatry research, 218(1-2), 54-60 (2014-05-06)
Multiple neurotrophic and/or growth factors, recently nominated as "angioneurins", play the key roles in mood modulation and neuroplasticity, and their dysfunction might be involved in the pathophysiology and treatment of mood disorders. We examined serum levels of vascular endothelial growth
Sandeep Kumar Vishwakarma et al.
Materials science & engineering. C, Materials for biological applications, 102, 34-44 (2019-05-31)
Spinal cord injury (SCI) is one of the most precarious conditions which have been one of the major reasons for continuous increasing mortality rate of SCI patients. Currently, there is no effective treatment modality for SCI patients posing major threat
Jharna R Das et al.
PloS one, 11(4), e0153837-e0153837 (2016-04-21)
Renal endothelial cells (REc) are the first target of HIV-1 in the kidney. The integrity of REc is maintained at least partially by heparin binding growth factors that bind to heparan sulfate proteoglycans located on their cell surface. However, previous
Yang Hu et al.
Molecular medicine reports, 13(1), 49-58 (2015-11-18)
Recent studies regarding regenerative medicine have focused on bone marrow mesenchymal stem cells (BMSCs), which have the potential to undergo neural differentiation, and may be transfected with specific genes. BMSCs can differentiate into neuron‑like cells in certain neurotropic circumstances in
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