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Merck
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문서

RAB0098

Sigma-Aldrich

Human M-CSF / CSF1 ELISA Kit

for serum, plasma, cell culture supernatant, urine

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모든 사진(2)

About This Item

UNSPSC 코드:
41116158
NACRES:
NA.32

종 반응성

human

포장

kit of 96 wells (12 strips x 8 wells)

기술

ELISA: suitable
capture ELISA: suitable

입력

sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.78-2000 pg/mL

검출 방법

colorimetric

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

human ... CSF1(1435)

일반 설명

M-CSF (colony stimulating factor 1) is a pleiotropic macrophage growth factor. It has a signal peptide, a 149-amino acid receptor-binding domain, a variable spacer region and a transmembrane region with a cytoplasmic tail. The human M-CSF receptor is a 972-amino acid glycosylated protein which consist of an extracellular region made of five immunoglobulin-like domains (D1–D5), a transmembrane region and an intracellular autocatalytic kinase domain. This gene is mapped to human chromosome p13-p21.
The Human MCSF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human MCSF in serum, plasma, cell culture supernatants and urine.

면역원

Recombinant Human MCSF

애플리케이션

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

생화학적/생리학적 작용

M-CSF (colony stimulating factor 1) plays a major role in the immune response, bone metabolism and the development of some cancers. It modulates macrophage survival, proliferation, differentiation and chemotaxis.

기타 정보

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

키트 구성품 역시 별도로 이용 가능함

제품 번호
설명
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

픽토그램

Corrosion
GHS05

신호어

Warning

유해 및 위험 성명서

H290

예방조치 성명서

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Reassignment of the human CSF1 gene to chromosome 1p13-p21.
Morris SW, et al.
Blood, 78(8), 2013-2020 (1991)
Combinatorial and computational approaches to identify interactions of macrophage colony-stimulating factor (M-CSF) and its receptor c-FMS.
Rosenfeld L, et al.
The Journal of Biological Chemistry, 290(43), 26180-26193 (2015)
Teresa Di Desidero et al.
Pharmacological research, 158, 104920-104920 (2020-05-29)
Anaplastic thyroid cancer (ATC) is a rare neoplasia with a poor prognosis. Proliferation and apoptosis assays were performed on ATC cell lines (8305C, 8505C) exposed to vinorelbine, lenvatinib, as well as to concomitant combinations. ABCB1, ABCG2 and CSF-1 mRNA expression

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