R3277
Rutaecarpine
>98% (HPLC)
동의어(들):
8,13-Dihydroindolo[2′,3′:3,4]pyrido[2,1-b]quinazolin-5(7H)-one, Rhetine, Rutecarpine
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모든 사진(1)
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5 MG
₩267,351
25 MG
₩561,498
About This Item
실험식(Hill 표기법):
C18H13N3O
CAS Number:
Molecular Weight:
287.32
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.25
추천 제품
Quality Level
분석
>98% (HPLC)
양식
solid
색상
white
solubility
DMSO: soluble 18 mg/mL (clear yellow solution)
H2O: insoluble
저장 온도
2-8°C
SMILES string
O=C1N2CCc3c([nH]c4ccccc34)C2=Nc5ccccc15
InChI
1S/C18H13N3O/c22-18-13-6-2-4-8-15(13)20-17-16-12(9-10-21(17)18)11-5-1-3-7-14(11)19-16/h1-8,19H,9-10H2
InChI key
ACVGWSKVRYFWRP-UHFFFAOYSA-N
유전자 정보
human ... CYP1A1(1543) , CYP1A2(1544) , CYP1B1(1545)
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생화학적/생리학적 작용
Delayed rectifier K+ channel blocker. Inhibits platelet aggregation; vasoldilator.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
가장 최신 버전 중 하나를 선택하세요:
시험 성적서(COA)
Lot/Batch Number
Jian-Zhe Li et al.
Canadian journal of physiology and pharmacology, 88(10), 949-959 (2010-10-22)
Dysfunction of capsaicin-sensitive sensory nerves is involved in cardiac remodeling, and rutaecarpine has been shown to exert a beneficial effect on cardiac function through activating the sensory nerves. This study was conducted to explore the potential inhibitory effect of rutaecarpine
Yong-Tai Zhang et al.
International journal of nanomedicine, 7, 2465-2472 (2012-06-09)
To investigate the cellular uptake of evodiamine and rutaecarpine in a microemulsion in comparison with aqueous suspensions and tinctures. A microemulsion was prepared using the dropwise addition method. Mouse skin fibroblasts were cultured in vitro to investigate the optimal conditions
Chuan-Qin Hu et al.
Journal of Asian natural products research, 14(4), 370-381 (2012-03-02)
A simple and sensitive high-performance liquid chromatographic method was developed for the simultaneous determination and pharmacokinetic analysis of seven alkaloids dehydroevodiamine (DHED), 10-hydroxyrutaecarpine (HDR), evodiamine (EDM), rutaecarpine (RCP), 1-methyl-2-n-nonyl-4(1H)quinolone (MNQ), evocarpine (ECP), and dihydroevocarpine (DHE), and two flavonoids isorhamnetin-7-O-rutinoside (RIM)
Meng-Ching Chen et al.
Journal of cellular biochemistry, 110(6), 1495-1503 (2010-05-27)
The incidence of thyroid cancer increases with age, and it is twice in women as common as in men. The undifferentiated thyroid cancer (UTC) is the most aggressive of all thyroid cancers. Unfortunately, there are almost no efficacious therapeutic modalities.
Shixi Xu et al.
Journal of ethnopharmacology, 139(2), 395-400 (2011-11-29)
Wu-Chu-Yu is a well-known herbal drug used for hypertension. Rutaecarpine and evodiamine are main bioactive components of the medicine. A sensitive and specific HPLC method was developed to analyze rutaecarpine (Rut) and evodiamine (Evo) in rat whole blood. The pharmacokinetics
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