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Merck
모든 사진(3)

문서

R0404

Sigma-Aldrich

Ramipril

≥98% (HPLC)

동의어(들):

Tritace, [2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid

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모든 사진(3)

About This Item

실험식(Hill 표기법):
C23H32N2O5
CAS Number:
87333-19-5
Molecular Weight:
416.51
MDL number:
MFCD00865775
UNSPSC 코드:
12352200
PubChem Substance ID:
24724586
NACRES:
NA.77

생물학적 소스

synthetic (organic)

분석

≥98% (HPLC)

형태

powder

색상

white

solubility

DMSO: ~18 mg/mL

주관자

Sanofi Aventis

저장 온도

2-8°C

SMILES string

O=C(N1[C@](CCC2)([H])[C@]2([H])C[C@H]1C(O)=O)[C@H](C)N[C@H](C(OCC)=O)CCC3=CC=CC=C3

InChI

1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1

InChI key

HDACQVRGBOVJII-JBDAPHQKSA-N

유전자 정보

human ... ACE(1636)

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관련 카테고리

생화학적/생리학적 작용

Angiotensin converting enzyme (ACE) inhibitor.

특징 및 장점

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

픽토그램

Health hazard
GHS08

신호어

Danger

유해 및 위험 성명서

H360FD

Hazard Classifications

Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

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문서 라이브러리 방문

Carla Zoja et al.
American journal of physiology. Renal physiology, 304(6), F808-F819 (2012-11-09)
Bardoxolone methyl is an antioxidant inflammation modulator acting through induction of Keap1-Nrf2 pathway. Results from a recent phase IIb clinical trial reported that bardoxolone methyl was associated with improvement in the estimated glomerular filtration rate in patients with advanced chronic
Joshua I Barzilay et al.
Clinical journal of the American Society of Nephrology : CJASN, 8(2), 233-240 (2012-11-28)
The microvascular circulation plays an important role in bone health. This study examines whether albuminuria, a marker of renal microvascular disease, is associated with incident hip and pelvic fractures. This study reanalyzed data from the Ongoing Telmisartan Alone and in
Guillaume Pare et al.
Pharmacogenetics and genomics, 23(9), 470-478 (2013-07-11)
The objective of this study was to identify genetic variants associated with angiotensin-converting enzyme (ACE) inhibitor-associated angioedema. We carried out a genome-wide association study in 175 individuals with ACE inhibitor-associated angioedema and 489 ACE inhibitor-exposed controls from Nashville (Tennessee) and
Daniela Dunkler et al.
JAMA internal medicine, 173(18), 1682-1692 (2013-08-14)
Type 2 diabetes mellitus and associated chronic kidney disease (CKD) have become major public health problems. Little is known about the influence of diet on the incidence or progression of CKD among individuals with type 2 diabetes. To examine the
G Castoldi et al.
American journal of nephrology, 37(1), 65-73 (2013-01-19)
Diabetic nephropathy is the main cause of end-stage renal disease. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), a physiological tetrapeptide hydrolyzed by the angiotensin-converting enzyme (ACE), has antifibrotic effects in the cardiovascular system and in the kidney in experimental models of hypertension, heart failure and
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