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Merck
모든 사진(3)

주요 문서

PRS4203

Sigma-Aldrich

Anti-Presenilin1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-γ-Secretase subunit presenilin-1, Anti-PS1, Anti-PSEN1, Anti-Presenilin 1

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크기 선택

100 μG
₩791,903

₩791,903


구입 가능 여부는 고객센터에 문의하십시오.


크기 선택

보기 변경
100 μG
₩791,903

About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

₩791,903


구입 가능 여부는 고객센터에 문의하십시오.

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

종 반응성

mouse, rat, human

기술

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... PSEN1(5663)

면역원

a 23 amino acid peptide from near the carboxy-terminus of human presenilin1.

결합

The action of this antibody can be blocked using blocking peptide SBP4203.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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관련 제품

제품 번호
설명
가격

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Weixi Feng et al.
Alzheimer's research & therapy, 12(1), 125-125 (2020-10-04)
Soluble beta-amyloid (Aβ) can be cleared from the brain through various mechanisms including enzymatic degradation, glial cell phagocytosis, transport across the blood-brain barrier, and glymphatic clearance. However, the relative contribution of each clearance system and their compensatory effects in delaying
Huang Huang et al.
Age (Dordrecht, Netherlands), 38(4), 303-322 (2016-07-22)
Transgenic APPSwe/PS1dE9 (APP/PS1) mice that overproduce amyloid beta (Aβ) are extensively used in the studies of pathogenesis and experimental therapeutics and new drug screening for Alzheimer's disease (AD). However, most of the current literature uses young or adult APP/PS1 mice.
Min Cao et al.
CNS neuroscience & therapeutics, 24(3), 202-211 (2017-12-24)
Social isolation increases the onset of Alzheimer's disease (AD). Environmental enrichment, a complicated social and physical construct, plays beneficial effects on brain plasticity and function. This study was designed to determine whether physical enrichment can reduce the deleterious consequences of social
Linmei Wang et al.
Brain pathology (Zurich, Switzerland), 29(2), 176-192 (2018-09-08)
The imbalance between production and clearance of amyloid-beta (Aβ) is a key step in the onset and development of Alzheimer's disease (AD). Therefore, reducing Aβ accumulation in the brain is a promising therapeutic strategy for AD. The recently discovered glymphatic
Tianqi Wang et al.
Aging and disease, 13(5), 1504-1522 (2022-10-04)
Non-cognitive behavioral and psychological symptoms often occur in Alzheimer's disease (AD) patients and mouse models, although the exact neuropathological mechanism remains elusive. Here, we report hyperactivity with significant inter-individual variability in 4-month-old APP/PS1 mice. Pathological analysis revealed that intraneuronal accumulation

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