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Merck
모든 사진(3)

주요 문서

PRS2437

Sigma-Aldrich

Anti-NOXA antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-APR, Anti-PMA-induced protein 1, Anti-PMAIP1, Anti-Phorbol-12-myristate-13-acetate-induced protein 1

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크기 선택

100 μG
₩863,867

₩863,867


구입 가능 여부는 고객센터에 문의하십시오.


크기 선택

보기 변경
100 μG
₩863,867

About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

₩863,867


구입 가능 여부는 고객센터에 문의하십시오.

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

종 반응성

mouse, rat, human

기술

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... PMAIP1(5366)
mouse ... Pmaip1(58801)

면역원

a synthetic peptide corresponding to 17 amino acids at the amino-terminus of mouse Noxa.

결합

The action of this antibody can be blocked using blocking peptide SBP2437.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Greta Del Mistro et al.
NPJ systems biology and applications, 4, 39-39 (2018-11-13)
Metastatic melanoma remains a life-threatening disease because most tumors develop resistance to targeted kinase inhibitors thereby regaining tumorigenic capacity. We show the 2nd generation hexavalent TRAIL receptor-targeted agonist IZI1551 to induce pronounced apoptotic cell death in mutBRAF melanoma cells. Aiming
Taryn G Aubrecht et al.
Cell death & disease, 9(11), 1121-1121 (2018-11-08)
Traumatic brain injury (TBI) activates multiple neuronal cell death mechanisms, leading to post-traumatic neuronal loss and neurological deficits. TBI-induced cell cycle activation (CCA) in post-mitotic neurons causes regulated cell death involving cyclin-dependent kinase (CDK) activation and initiation of an E2F
Patryk Janus et al.
Cell death and differentiation, 27(7), 2280-2292 (2020-01-31)
Heat shock can induce either cytoprotective mechanisms or cell death. We found that in certain human and mouse cells, including spermatocytes, activated heat shock factor 1 (HSF1) binds to sequences located in the intron(s) of the PMAIP1 (NOXA) gene and
Ines Müller et al.
Molecular cell, 77(5), 970-984 (2020-01-27)
Cytosolic caspase-8 is a mediator of death receptor signaling. While caspase-8 expression is lost in some tumors, it is increased in others, indicating a conditional pro-survival function of caspase-8 in cancer. Here, we show that tumor cells employ DNA-damage-induced nuclear

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