PLA0029

Rabbit anti-BLM Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• 동의어(들): BS, Bloom syndrome, DNA helicase, RECQ2, RECQL2, RECQL3, RecQ helicase-like, RecQ-like type 2, recQ protein-like 3
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity purified immunoglobulin
• 항체 생산 유형: primary antibodies
• Grade: Powered by Bethyl Laboratories, Inc.
• 종 반응성: human, mouse
• 기술: immunoprecipitation (IP): 2-10 μg/mg; western blot: 1:1,000- 1:10,000
• 수납 번호(accession number): NP_000048.1
• UniProt 수납 번호: P54132
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: rabbit ... BLM(641)

설명

면역원

The epitope recognized by PLA0029 maps to a region between residue 1325 and the C-terminus (residue 1417) of human Bloom Syndrome using the numbering given in entry NP_000048.1 (GeneID 641).

물리적 형태

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

기타 정보

Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable