P9864

PTP-β human

≥90%, recombinant, expressed in E. coli K12, GST-tagged, buffered aqueous glycerol solution, ≥50,000 units/mg protein

• 동의어(들): Protein Tyrosine Phosphatase-β
• CAS Number: 300853-81-0
• MDL number: MFCD02688688
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: human
• Quality Level: 200
• 재조합: expressed in E. coli K12
• 분석: ≥90%
• 양식: buffered aqueous glycerol solution
• 특이 활성도: ≥50,000 units/mg protein
• 분자량: ~250 kDa
• UniProt 수납 번호: P23467
• 응용 분야: cell analysis
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... PTPRB(5787)

설명

일반 설명

Protein tyrosine phosphatase, receptor type B (PTPRB), also known as vascular endothelial-protein-tyrosine phosphatase (VE-PTP), might have a role in remodeling of blood vessels and in angiogenesis. The gene encoding it is localized on human chromosome 12q15.[1] It is also important for endothelial cell migration.[2] The protein also controls the phosphorylation state of the angiopoietin receptor, Tie-2. PTPRB may modulate sodium channels by influencing the tyrosine phosphorylation status.[3][4]

생화학적/생리학적 작용

Dephosphorylates tyrosine proteins.

단위 정의

One unit of PTP-β will hydrolyze 1.0 nanomole of p-nitrophenyl phosphate per min at 30 °C.

물리적 형태

solution in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCL, 3 mM DTT, 16 mM glutathione and 20% glycerol

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable