The pH of a solution containing Poloxamer 188 may change over time due to factors such as hydrolysis or oxidation. The pH stability of Poloxamer 188 solutions has not been conducted. However, end users are encouraged to periodically monitor the solutions to ensure their stability and efficacy.
추천 제품
설명
non-ionic
Quality Level
무균
sterile-filtered
제품 라인
BioReagent
분자량
average mol wt 8350
농도
10%
기술
cell culture | insect: suitable
불순물
endotoxin, tested
전이 온도
cloud point ≥100
HLB
29
SMILES string
O2C(C2)C.O1CC1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
일반 설명
Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropylene flanked at ends by hydrophilic polyoxyethylene.[1]
애플리케이션
A nonionic copolymer surfactant
생화학적/생리학적 작용
Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence.[1][2] P-188 exhibits low toxicity and may be used in oral drug delivery.
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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