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Merck
모든 사진(1)

주요 문서

P3494

Sigma-Aldrich

Potassium clavulanate

from Streptomyces clavuligerus

동의어(들):

Clavulanate potassium

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About This Item

실험식(Hill 표기법):
C8H8NO5K
CAS Number:
Molecular Weight:
237.25
EC Number:
MDL number:
UNSPSC 코드:
51101500
PubChem Substance ID:
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생물학적 소스

Streptomyces clavuligerus

항생제 활성 스펙트럼

Gram-negative bacteria
Gram-positive bacteria

동작 모드

cell wall synthesis | interferes

저장 온도

2-8°C

SMILES string

[K+].[H][C@@]12CC(=O)N1[C@@H](C([O-])=O)C(\O2)=C\CO

InChI

1S/C8H9NO5.K/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h1,6-7,10H,2-3H2,(H,12,13);/q;+1/p-1/b4-1-;/t6-,7-;/m1./s1

InChI key

ABVRVIZBZKUTMK-JSYANWSFSA-M

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생화학적/생리학적 작용

β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.
In combination with penicillin group antibiotics to inhibit specific (group 2) β-penicillinases and cephalosporinases.

관련 제품

제품 번호
설명
가격

픽토그램

FlameHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Flam. Sol. 2 - Resp. Sens. 1 - Self-heat. 2 - Skin Sens. 1

보충제 위험성

Storage Class Code

4.2 - Pyrophoric and self-heating hazardous materials

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Gustavo Jesus Vazquez-Zapien et al.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 60(1), 189-194 (2019-07-03)
Kidney diseases are a global public health problem. Despite significant advances in the understanding of renal failure (RF) and replacement therapies, this condition carries a series of complications and the life's quality of patients decreases. Differentiation capability of stem cells
Yoram Fleissig et al.
Oral surgery, oral medicine, oral pathology and oral radiology, 113(3), e1-e3 (2012-06-09)
A 58-year-old woman presented to the Oral and Maxillofacial Surgery Clinic experiencing severe limited mouth opening and exposed bone in the socket of the right mandibular third molar 8 months following the extraction of the tooth. The patient had been
Oriol Mitjà et al.
The American journal of tropical medicine and hygiene, 86(6), 1043-1045 (2012-06-06)
We report the first documented case of a mycetoma caused by Nocardia yamanashiensis after the initial description of this species. The 16S-rRNA gene sequence analysis was used to identify the novel species, which showed a similarity of 99.9% to the
Ximena Gonzalo et al.
The Journal of antimicrobial chemotherapy, 68(2), 366-369 (2012-10-17)
To: (i) assess if amoxicillin/clavulanate is a useful option for the management of multidrug-resistant/extensively drug-resistant tuberculosis (MDR/XDR-TB); (ii) assess if meropenem/clavulanate is active against Mycobacterium tuberculosis at concentrations achievable in vivo; and (iii) determine whether there was inhibition of meropenem/clavulanate
B R Smith et al.
Drug intelligence & clinical pharmacy, 19(6), 415-420 (1985-06-01)
Potassium clavulanate is a novel beta-lactamase inhibitor, which, in combination, expands the spectrum of amoxicillin to include many amoxicillin-resistant organisms. Potassium clavulanate is excreted 30-50 percent unchanged renally and its plasma time-course parallels that of amoxicillin. Several studies suggest that

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