P1306

Peptide YY human

≥97% (HPLC), synthetic

• 동의어(들): PYY, Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH₂
• 실험식(Hill 표기법): C₁₉₄H₂₉₅N₅₅O₅₇
• CAS Number: 118997-30-1
• Molecular Weight: 4309.75
• MDL number: MFCD00081843
• UNSPSC 코드: 51111800
• NACRES: NA.32

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥97% (HPLC)
• 형태: solid
• UniProt 수납 번호: P10082
• 저장 온도: −20°C
• 유전자 정보: human ... PYY(5697)

설명

Amino Acid Sequence

Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2

일반 설명

Human peptide YY (PYY) is secreted by mucosal L cells in the distal ileum, colon and rectum. It consists of 36 amino acids. The gene encoding PYY is localized on human chromosome 17q21.1.

애플리케이션

Peptide YY human has been used as a supplement in Roswell Park Memorial Institute medium (RPMI medium) to culture pancreatic duct-derived cells.

생화학적/생리학적 작용

Gut hormone that inhibits both secretin and cholecystokinin-stimulated pancreatic secretion. Endogenous nonselective agonist at NPY receptors.

Human peptide YY (PYY) has a role in food ingestion, gut motility and insulin secretion. The protein suppresses appetite. It has been associated with obesity and type 2 diabetes. PYY also has a role in energy homeostasis.

기타 정보

Lyophilized from 0.1% TFA in H2O

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)