추천 제품
생물학적 소스
rabbit
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
lyophilized powder
종 반응성
human, rat
기술
western blot (chemiluminescent): 1:200 using rat brain membranes
UniProt 수납 번호
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
rat ... Kcnn2(54262)
일반 설명
Potassium calcium-activated channel subfamily N member 2 (KCNN2) or SK2 is expressed in rat Purkinje cells. The gene encoding this protein is localized on rat chromosome 18q11.
면역원
synthetic peptide corresponding to amino acids 542-559 of rat potassium channel SK2.
애플리케이션
Anti-Potassium Channel SK2 (Apamin-Sensitive Conductance Ca2+-Dependent K+ Channel, KCa2, Kcnn2, SKCa2) antibody produced in rabbit has been used for immunohistochemistry and immunofluorescence.
생화학적/생리학적 작용
Potassium calcium-activated channel subfamily N member 2 (KCNN2) or SK2 has a role in the modulation of intrinsic excitability of neurons and Purkinje cells. It also has a role in synaptic transmission and plasticity. SK2 promotes hippocampus-dependent learning and memory in the mammalian brain.
물리적 형태
Lyophilized at 0.3-1.4 mg/mL from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.025% - 0.050% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Neurotransmitter modulation of small conductance Ca2+-activated K+ (SK) channels by regulation of Ca2+ gating
Francois M
Neuron (2008)
Mark J Shen et al.
Heart rhythm, 10(6), 910-915 (2013-01-30)
Small conductance calcium-activated potassium (SK) channels are responsible for afterhyperpolarization that suppresses nerve discharges. To test the hypothesis that low-level vagus nerve stimulation (LL-VNS) leads to the upregulation of SK2 proteins in the left stellate ganglion. Six dogs (group 1)
SK2 channel expression and function in cerebellar Purkinje cells
Eric Hosy
The Journal of Physiology (2011)
Low-Level Vagus Nerve Stimulation Upregulates Small Conductance Calcium Activated Potassium Channels in the Stellate Ganglion
Mark J. Shen
Heart Rhythm : the Official Journal of the Heart Rhythm Society (2013)
Deletion of the Ca2+-activated potassium (BK) a-subunit but not the BK?1-subunit leads to progressive hearing loss
Lukas Ruttiger
Proceedings of the National Academy of Sciences of the USA (2004)
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