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Merck
모든 사진(1)

문서

N6132

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide 3′-phosphate reduced form sodium salt

≥90%

동의어(들):

3′-NADPH, 3′-TPNH

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C21H30N7O17P3
Molecular Weight:
745.42
EC Number:
220-163-3
MDL number:
MFCD00135611
UNSPSC 코드:
41106305
PubChem Substance ID:
24897769

분석

≥90%

형태

solid

저장 온도

−20°C

SMILES string

[Na].NC(=O)C1=CN(C=CC1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(OP(O)(O)=O)C3O)n4cnc5c(N)ncnc45)C(O)C2O

InChI

1S/C21H30N7O17P3.Na.H/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;

InChI key

ZQJHSLJFGRIJQN-UHFFFAOYSA-N

애플리케이션

β-Nicotinamide adenine dinucleotide 3′-phosphate reduced (3′-NADPH) may be used as an inhibitory analogue to study the specificity and kinetics of NADP+/NADPH-dependent enzymes. 3′-NADPH is used to study copper ion aggregation of prion protein.

기타 정보

Analog of β-NADPH, chemically reduced

주의사항

This is not the common β-NADPH required in the usual enzyme systems.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

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문서 라이브러리 방문

Noriyuki Shiraishi et al.
The Journal of biological chemistry, 281(46), 34880-34887 (2006-09-23)
Recent studies have demonstrated that the octapeptide repeats of the N-terminal region of prion protein may be responsible for de novo generation of infectious prions in the absence of template. Here we demonstrate that PrP-(23-98), an N-terminal portion of PrP
A M Dhalla et al.
Biochemistry, 34(16), 5390-5402 (1995-04-25)
The Escherichia coli MurB gene encoding UDP-N-acetylenolpyruvylglucosamine reductase was expressed to a level of approximately 100 mg/L as a fusion construct with maltose binding protein. Rapid affinity purification, proteolysis, and anion exchange chromatography yielded homogeneous enzyme containing 1 mol/mol bound
Chikako Fukuda et al.
Applied and environmental microbiology, 73(17), 5447-5452 (2007-07-10)
NADP(H) phosphatase has not been identified in eubacteria and eukaryotes. In archaea, MJ0917 of hyperthermophilic Methanococcus jannaschii is a fusion protein comprising NAD kinase and an inositol monophosphatase homologue that exhibits high NADP(H) phosphatase activity (S. Kawai, C. Fukuda, T.

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