생물학적 소스
goat
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
lyophilized powder
종 반응성
mouse
기술
indirect ELISA: 0.5-1 μg/mL using recombinant mouse netrin-G1a
western blot: 0.1-0.2 μg/mL using recombinant mouse netrin-G1a
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
mouse ... Ntng1(80883)
일반 설명
Netrin-G1a (NTNG1) is also known as laminet 1. It is expressed in axons and is a trans-synaptic adhesion protein. NTNG1 is part of the glycosylphosphatidylinositol-anchored subfamily of the UNC-6/netrin family.
특이성
This antibody shows less than 2% cross-reactivity with rmNetrin-1, rhNetrin-2, and rhNetrin-4.
면역원
purified, insect cell line Sf 21-derived, recombinant mouse Netrin-G1a.
생화학적/생리학적 작용
Netrin-G1a (NTNG1) stimulates the outgrowth of axons in the thalamo-cortical region of the brain and helps to excite the post-synaptic regions.
물리적 형태
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
Hiroshi Matsukawa et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(47), 15779-15792 (2014-11-21)
Synaptic cell adhesion molecules are increasingly gaining attention for conferring specific properties to individual synapses. Netrin-G1 and netrin-G2 are trans-synaptic adhesion molecules that distribute on distinct axons, and their presence restricts the expression of their cognate receptors, NGL1 and NGL2
Kunio Yaguchi et al.
Molecular brain, 7, 19-19 (2014-03-20)
Higher brain function is supported by the precise temporal and spatial regulation of thousands of genes. The mechanisms that underlie transcriptional regulation in the brain, however, remain unclear. The Ntng1 and Ntng2 genes, encoding axonal membrane adhesion proteins netrin-G1 and
Elena Seiradake et al.
The EMBO journal, 30(21), 4479-4488 (2011-09-29)
Brain wiring depends on cells making highly localized and selective connections through surface protein-protein interactions, including those between NetrinGs and NetrinG ligands (NGLs). The NetrinGs are members of the structurally uncharacterized netrin family. We present a comprehensive crystallographic analysis comprising
활성 필터
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