N3143
Nalidixic acid sodium salt
powder
동의어(들):
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid sodium salt
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C12H11N2NaO3
CAS Number:
Molecular Weight:
254.22
Beilstein:
3580062
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
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추천 제품
무균
γ-irradiated
양식
powder
항생제 활성 스펙트럼
Gram-negative bacteria
Gram-positive bacteria
동작 모드
DNA synthesis | interferes
enzyme | inhibits
SMILES string
[Na+].CCN1C=C(C([O-])=O)C(=O)c2ccc(C)nc12
InChI
1S/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1
InChI key
ROKRAUFZFDQWLE-UHFFFAOYSA-M
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일반 설명
Chemical structure: quinolone
애플리케이션
Recommended for use in molecular biology applications at 15 μg/ml
생화학적/생리학적 작용
Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.
재구성
Prepare stock solutions directly in the vial with sterile water (5-50 mg/ml). Stock solutions should be stored at −20 °C.
교체됨
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2 - Resp. Sens. 1 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Anna Duse et al.
Journal of dairy science, 98(9), 6387-6398 (2015-07-21)
Quinolone resistance may emerge in gut bacteria (e.g., in Escherichia coli) of animals. Such bacteria could cause infections in the animal itself or be transmitted to humans via the food chain. Quinolone resistance is also observed in fecal E. coli
Jing Wang et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(11), 14631-14644 (2020-09-13)
During spaceflight, astronauts are subjected to various physical stressors including microgravity, which could cause immune dysfunction and thus potentially predispose astronauts to infections and illness. However, the mechanisms by which microgravity affects innate immunity remain largely unclear. In this study
Mohamed Nawaz et al.
International journal of food microbiology, 155(3), 179-184 (2012-03-13)
A study was undertaken to isolate and characterize tetracycline and nalidixic acid-resistant Klebsiella spp. in farm-raised, imported shrimp sold in the United States. Sixty-seven multiple antibiotic-resistant Klebsiella spp. strains were isolated from imported shrimp samples. Using morphological and biochemical methods
Xiangqun Fan et al.
Environmental science and pollution research international, 20(6), 3649-3656 (2012-11-07)
The Fenton-like degradation of nalidixic acid was studied in this work. The effects of Fe(3+) concentration and initial H(2)O(2) concentration were investigated. Increasing the initial H(2)O(2) concentration enhances the degradation and mineralization efficiency for nalidixic acid, while Fe(3+) shows an
Atefeh Abouzarzadeh et al.
Journal of molecular recognition : JMR, 25(7), 404-413 (2012-06-27)
For the first time in this work, uniform molecularly imprinted polymer (MIP) nanoparticles were prepared using nalidixic acid as a template. The MIP nanoparticles were successfully synthesized by precipitation polymerization applying methacrylic acid (MAA) as a functional monomer and trimethylolpropane
활성 필터
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