추천 제품
사용
sufficient for 100 colorimetric tests
응용 분야
cosmetics
food and beverages
검출 방법
colorimetric
관련 질환(들)
endocrinological disorders, diabetes; cancer
저장 온도
−20°C
일반 설명
L(+)-Lactate is a metabolic compound formed in animals by the action of the enzyme Lactate Dehydrogenase. Lactate is produced in proliferating cells and during anaerobic conditions such as exercise. Abnormally high concentrations of lactate have been related to pathological conditions such as cancer, diabetes, and lactate acidosis. L(+)-Lactate is the major stereoisomer of lactate formed in human intermediary metabolism and is present in blood at levels of around 1-2 mmol/L. This kit provides a convenient means for detecting L(+)-Lactate in biological samples.
애플리케이션
Lactate Assay Kit II has been used to measure the levels of lactate in samples.
적합성
Suitable for detecting L(+)-Lactate in culture medium, fermentation medium, blood and cells.
원리
Lactate concentration is determined by an enzyme assay, which results in a colorimetric (450 nm) product, proportional t the lactate present. There is no need of pretreatment or purification of samples. Typical sensitivities of detection are between 0.02-10 mM of lactate.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Metabolic engineering of Methanosarcina acetivorans for lactate production from methane
McAnulty M J, et al.
Biotechnology and Bioengineering, 114(4), 852-861 (2017)
DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders.
Jouroukhin Y, et al.
Translational Psychiatry, 8(1), 76-76 (2018)
Camaron R Hole et al.
Nature communications, 10(1), 2955-2955 (2019-07-06)
Dendritic cells (DCs), a vital component of the innate immune system, are considered to lack antigen specificity and be devoid of immunological memory. Strategies that can induce memory-like responses from innate cells can be utilized to elicit protective immunity in
Satyendra C Tripathi et al.
Cancer research, 77(16), 4414-4425 (2017-06-25)
Despite favorable responses to initial therapy, small-cell lung cancer (SCLC) relapse occurs within a year and exhibits resistance to multiple drugs. Because of limited accessibility of patient tissues for research purposes, SCLC patient-derived xenografts (PDX) have provided the best opportunity
Yan Jouroukhin et al.
Translational psychiatry, 8(1), 76-76 (2018-04-13)
Our knowledge of how genetic risk variants contribute to psychiatric disease is mainly limited to neurons. However, the mechanisms whereby the same genetic risk factors could affect the physiology of glial cells remain poorly understood. We studied the role of
문서
Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.
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