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Merck
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주요 문서

M3781

Sigma-Aldrich

6α-Methylprednisolone 21-hemisuccinate sodium salt

lyophilized powder

동의어(들):

6α-Methylprednisolone sodium succinate, MPSL, 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate

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크기 선택

25 MG
₩128,398
250 MG
₩774,953
1 G
₩1,890,133

₩128,398


예상 입고일2025년 2월 17일세부사항


벌크 견적 요청

크기 선택

보기 변경
25 MG
₩128,398
250 MG
₩774,953
1 G
₩1,890,133

About This Item

Linear Formula:
C26H33O8Na
CAS Number:
Molecular Weight:
496.53
EC Number:
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
NACRES:
NA.77

₩128,398


예상 입고일2025년 2월 17일세부사항


벌크 견적 요청

생물학적 소스

synthetic

Quality Level

무균

non-sterile

분석

≥98.00% (TLC)

양식

lyophilized powder

기술

toxicology assay: suitable

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

배송 상태

ambient

저장 온도

room temp

SMILES string

[Na+].C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)CCC([O-])=O)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14

InChI

1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1

InChI key

FQISKWAFAHGMGT-SGJOWKDISA-M

유전자 정보

human ... NR3C1(2908)

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관련 카테고리

애플리케이션

6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.[1]

생화학적/생리학적 작용

Glucocorticoid with slightly longer half-life than that of prednisolone.

물리적 형태

Lyophilized containing ~5% phosphate buffer salts.

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Carc. 2 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Julie M Jones et al.
The Journal of the American Osteopathic Association, 112(2), 90-92 (2012-02-15)
Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a type III hypersensitivity reaction characterized by urticaria with persistent acquired hypocomplementemia. Although HUVS is uncommon, it is important for physicians to be familiar with this disease, as the initial presentation is often life-threatening
[The issue of methylprednisolone sodium succinate dosage for use].
Yu-cai Zhang et al.
Zhonghua er ke za zhi = Chinese journal of pediatrics, 49(5), 389-390 (2011-06-01)
Dapsone hypersensitivity syndrome complicated by Scedosporium apiospermum pneumonia in an immunocompetent patient.
L Ceccarelli et al.
Infection, 40(4), 459-462 (2011-11-30)
Rina Ulmansky et al.
Journal of controlled release : official journal of the Controlled Release Society, 160(2), 299-305 (2012-01-10)
We have previously shown that intravenous (i.v.) treatment with sterically stabilized nano-liposomes (NSSL) actively remote-loaded with the glucocorticoid (GC) methylprednisolone hemisuccinate (NSSL-MPS) or betamethasone hemisuccinate (NSSL-BMS) significantly decreased severity of adjuvant arthritis in Lewis rats (a model of human rheumatoid
Julio Urrutia et al.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 16(4), 439-442 (2011-04-30)
The effect of corticosteroids on spinal fusion healing has not yet been determined. To evaluate the effect of corticosteroids on lumbar spinal fusion we designed a randomized, placebo-controlled animal study using high-dose methylprednisolone sodium succinate, which is widely used in

질문

  1. How long is product M3781 good for once it is reconstituted in water?

    1 답변
    1. There is no available information on the duration for which the product remains viable once reconstituted, as it was not tested for this purpose.

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