L9150

N-Lauroylsarcosine sodium salt

detergent for use in cell lysis

• 동의어(들): Sodium lauroyl sarcosinate, N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL
• Linear Formula: CH₃(CH₂)₁₀CON(CH₃)CH₂COONa
• CAS Number: 137-16-6
• Molecular Weight: 293.38
• Beilstein: 5322974
• EC Number: 205-281-5
• MDL number: MFCD00042728
• UNSPSC 코드: 12161902
• PubChem Substance ID: 57654340
• NACRES: NA.52

속성

• Grade: Molecular Biology; for molecular biology
• 설명: anionic
• 제품 라인: BioReagent
• 분석: ≥94%
• 양식: powder
• 분자량: micellar avg mol wt 600
• 응집 번호: 2
• 기술: protein purification: suitable; protein quantification: suitable
• CMC: 14.6 mM (20-25°C)
• solubility: H₂O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
• 외래 활성: DNase, RNase, none detected
• 저장 온도: room temp
• SMILES string: [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O
• InChI: 1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1
• InChI key: KSAVQLQVUXSOCR-UHFFFAOYSA-M

설명

일반 설명

Sodium lauroyl sarcosinate, the sodium salt of an acyl derivative of sarcosine—a natural amino acid occurring in muscles and body tissues—stands out as a valuable component in molecular biology, biochemical, and cell biology research. Derived from a natural fatty acid and the amino acid derivative sarcosine, N-Lauroylsarcosine is a biodegradable anionic surfactant usually synthesized through acylation and neutralization reactions involving lauric acid and sodium sarcosine.

This amino acid-type anionic surfactant, also recognized as a fatty acid amide and detergent, exhibits protein denaturant potency and has been integrated into lysing solutions, such as the cornet assay. Its application extends to lysing protoplasts for chromosomal DNA isolation from Streptococcus mutans. Notably, Lauroylsarcosine Sodium Salt, characterized by its ionic detergent properties, is commonly employed for purifying membrane proteins. Additionally, Sodium Lauroyl Sarcosine also plays a crucial role in concentrated salt solutions, facilitating cell lysis in RNA purification protocols and membrane solubilization. Whether it′s breaking down cell structures or facilitating membrane protein purification, this mild surfactant proves valuable in various applications within the realms of biology and biochemistry.

애플리케이션

Suitable for

• solubilization and separation of membrane proteins
• lysis of cells during the isolation of RNA
• inhibition of hexokinase

특징 및 장점

• Suitable for Molecular Biology, Biochemical and Cell Biology research
• Can be used for Protein Purification and Quantification
• High purity product for research applications

기타 정보

Anionic surfactant.

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안전성 정보

• 픽토그램: GHS06,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H315,H318,H330
• 예방조치 성명서: P260 - P264 - P280 - P302 + P352 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 1
• Flash Point (°F): 512.6 °F - closed cup
• Flash Point (°C): 267 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)