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Merck
모든 사진(2)

문서

L8045

Sigma-Aldrich

Liquiritin

from Glycyrrhizae root (licorice root), ≥98% (HPLC)

동의어(들):

4′,7-Dihydroxyflavanone 4′-glucoside, Liquiritoside

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About This Item

실험식(Hill 표기법):
C21H22O9
CAS Number:
Molecular Weight:
418.39
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.25

생물학적 소스

Glycyrrhizae root (licorice root)

분석

≥98% (HPLC)

형태

powder

응용 분야

metabolomics
vitamins, nutraceuticals, and natural products

저장 온도

2-8°C

SMILES string

O=C1C2=CC=C(O)C=C2O[C@H](C3=CC=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C=C3)C1

InChI

1S/C21H22O9/c22-9-17-18(25)19(26)20(27)21(30-17)28-12-4-1-10(2-5-12)15-8-14(24)13-6-3-11(23)7-16(13)29-15/h1-7,15,17-23,25-27H,8-9H2/t15-,17+,18+,19-,20+,21+/m0/s1

InChI key

DEMKZLAVQYISIA-ZRWXNEIDSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Liquiritin is a type of flavone, present as an active ingredient in Glycyrrhiza uralensis and Glycyrrhiza glabra extract. It is a constituent of many traditional Chinese medicine formulas popularly used as a cure for asthma, peptic ulcers, and cough.

애플리케이션

Liquiritin has been used to analyze the extract of Glycyrrhiza uralensis and examine its components for anti-Hepatitis C virus activity.

생화학적/생리학적 작용

Liquiritin has been attributed to show antidepressant-like and antioxidant activity. It causes apoptosis in cell lines having gastric cancer and promyelocytic leukemia. Liquiritin also demonstrates neurotrophic effects and hence has been considered as a potential contender for the management of different neurodegenerative diseases. It shows an anti-inflammatory property with protection to the liver against oxidative damage. It has depigmenting ability and is a potential medicine for melasma.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Zheng-Ai Chen et al.
Cytotechnology, 60(1-3), 125-132 (2009-10-01)
Neurite outgrowth and neuronal differentiation play a crucial role in the development of the nervous system. Understanding of neurotrophins induced neurite outgrowth was important to develop therapeutic strategy for axon regeneration in neurodegenerative diseases as well as after various nerve
Zhiyu Zhao et al.
Behavioural brain research, 194(1), 108-113 (2008-07-29)
Many flavonoids extracted from nature plants have been reported to exert antidepressant-like effect in animal studies. The present study was designed to observe the effects of liquiritin, a flavone compound derived from Glycyrrhiza uralensis, on the behaviors of chronic variable
Qiuyan Guo et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 123, 109812-109812 (2020-01-17)
Wu-tou decoction (WTD), a classic Traditional Chinese medicine formula, has been extensively used in the treatment of neuropathic pain (NP) such as chronic inflammatory pain, trigeminal neuralgia, and cancer-induced pain. Our previous studies have shown that the severity of mechanical
M Amer et al.
International journal of dermatology, 39(4), 299-301 (2000-05-16)
Twenty women with a clinical diagnosis of melasma were treated with liquiritin cream on one side of the face and with a vehicle cream on the other side twice daily for 4 weeks. Patients were advised to avoid sun exposure
Ji-Yeon Yu et al.
Molecules (Basel, Switzerland), 20(7), 13041-13054 (2015-07-25)
This study provides the scientific basis for the anti-inflammatory effects of licorice extract in a t-BHP (tert-butyl hydrogen peroxide)-induced liver damage model and the effects of its ingredients, glycyrrhizic acid (GA), liquiritin (LQ) and liquiritigenin (LG), in a lipopolysaccharide (LPS)-stimulated

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