K3125

Kojic acid

≥98.5% (HPLC), powder, tyrosinase inhibitor

• 동의어(들): 2-Hydroxymethyl-5-hydroxy-γ-pyrone, 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone
• 실험식(Hill 표기법): C₆H₆O₄
• CAS Number: 501-30-4
• Molecular Weight: 142.11
• Beilstein: 120895
• EC Number: 207-922-4
• MDL number: MFCD00006580
• UNSPSC 코드: 12352106
• PubChem Substance ID: 24896226
• NACRES: NA.77

속성

• product name: Kojic acid,
• 분석: ≥98.5% (HPLC)
• 형태: powder
• mp: 152-155 °C (lit.)
• SMILES string: OCC1=CC(=O)C(O)=CO1
• InChI: 1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
• InChI key: BEJNERDRQOWKJM-UHFFFAOYSA-N

설명

애플리케이션

Kojic acid has been used:

• as an inhibitor of tyrosinase in guinea pigs pigmented hyperopic (PH)
• as a reference inhibitor standard for screening tyrosinase inhibition
• as a positive control for inhibition of tyrosinase in B16F10 melanoma cells

생화학적/생리학적 작용

Kojic acid is derived from some fungal species such as, Aspergillus, Acetobacter and Penicillium.. It halts melanin synthesis by inhibiting tyrosinase enzyme. It is used in the preparation of skin whitening cosmetics. However, kojic acid usage is minimal in cosmetics, as it induces skin irritation by its unstability and cytotoxic nature during long storage. It is an antioxidant and elicits radioprotective effects on chelating with manganese and zinc.

Tyrosinase inhibitor.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)