Regarding the location of the FITC label and any effects on activity, there is no specific description available on where the FITC label is positioned on FITC-insulin. However, in practice, there are only three potential sites where the FITC can derivatize the insulin. These locations include both of the N-terminal residues, off the free amine, and the Lysine at the 3rd position near the C-terminus of the B-chain.
추천 제품
재조합
expressed in yeast
Quality Level
양식
lyophilized powder
solid
구성
Insulin, ≥75% biuret
라벨링 범위
≥1 mol FITC per mol insulin
배송 상태
dry ice
dry ice
저장 온도
−20°C
−20°C
일반 설명
Insulin is a polypeptide hormone mainly secreted from pancreas when glucose level changes in the plasma. It is an anabolic hormone and enhances the generation of storage substances, for instance glycogen, fat and protein. It also induces glucose uptake by peripheral tissues, thereby controlling glucose levels in the plasma. Its main sites of action are liver, adipose tissue and muscle.[1]
애플리케이션
Insulin-FITC labeled human has been used in primary endothelial cells from human adipose tissue microvasculature (HAMEC) to study insulin transcytosis.[2]
물리적 형태
Lyophilized powder containing sodium phosphate buffer salts
Storage Class Code
11 - Combustible Solids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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시험 성적서(COA)
Lot/Batch Number
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