H3661

4′-Hydroxydiclofenac

≥98% (HPLC)

• 동의어(들): 4′-Hydroxy Diclofenac, [2-(2,6-Dichloro-4-hydroxy-phenylamino)phenyl]acetic acid
• 실험식(Hill 표기법): C₁₄H₁₁Cl₂NO₃
• CAS Number: 64118-84-9
• Molecular Weight: 312.15
• Beilstein: 4198042
• MDL number: MFCD01671980
• UNSPSC 코드: 12161501
• PubChem Substance ID: 24895589
• NACRES: NA.47

속성

• Quality Level: 200
• 분석: ≥98% (HPLC)
• 포장: vial of 5 mg
• 저장 온도: −20°C
• SMILES string: OC(=O)Cc1ccccc1Nc2c(Cl)cc(O)cc2Cl
• InChI: 1S/C14H11Cl2NO3/c15-10-6-9(18)7-11(16)14(10)17-12-4-2-1-3-8(12)5-13(19)20/h1-4,6-7,17-18H,5H2,(H,19,20)
• InChI key: KGVXVPRLBMWZLG-UHFFFAOYSA-N

설명

일반 설명

4′-Hydroxydiclofenac is an important metabolite of aceclofenac, seen mainly in rats. It is the important oxidative metabolite found in urine.

CYP2C9 metabolite of diclofenac.

애플리케이션

4′-Hydroxydiclofenac has been used to investigate the effect of gentiopicroside (GE) on human cytochrome P450 enzymes in vitro. It has also been used as an enzyme marker to study its metabolic activities in different in vitro liver models.

안전성 정보

• 픽토그램: GHS06,GHS05,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H301,H315,H318,H335,H410
• 예방조치 성명서: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges