H3040

HER2 (676-end), active, GST tagged human

PRECISIO^® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

• 동의어(들): ERBB2, NEU, NGL, TKR1, c-erb B2
• UNSPSC 코드: 51111800
• NACRES: NA.32

속성

• 재조합: expressed in baculovirus infected Sf9 cells
• Quality Level: 200
• 제품 라인: PRECISIO^® Kinase
• 분석: ≥70% (SDS-PAGE)
• 형태: buffered aqueous glycerol solution
• 특이 활성도: 9-13 nmol/min·mg
• 분자량: ~116 kDa
• UniProt 수납 번호: P04626
• 관련 질환(들): cancer (breast)
• 배송 상태: dry ice
• 저장 온도: −70°C
• 유전자 정보: human ... ERBB2(2064)

설명

일반 설명

HER2 (eceptor tyrosine-protein kinase erbB-2) is a cell surface-associated glycoprotein tyrosine kinase receptor.

생화학적/생리학적 작용

HER2 (receptor tyrosine-protein kinase erbB-2) is an oncogene and is up-regulated in breast cancer. Overexpression of HER2 is associated with uncontrolled cellular proliferation, resistance to apoptotic cell death and increased motility.

물리적 형태

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

법적 정보

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)